No - integrations are how Home Assistant knows how to “talk” to that device.
Now, there may be (I haven’t searched extensively) third party (aka custom) integrations that support these. For example:
- https://community.home-assistant.io/t/does-anyone-own-an-ee-plusnet-smarthub/478617
- https://community.home-assistant.io/t/custom-component-tp-link-router-integration/638647
If in doubt, hit up Google for Home Assistant name of device and see what you find