Just in case you are doing this manually, I’m pretty sure all four of these automated backup solutions also have the option to exclude addons and folders of your choosing:
To a NAS: Samba Backup: Create and store snapshots on a Samba share
To Goggle Drive: Hass.io Add-on: Hass.io Google Drive Backup
To DropBox: Hass.io Add-on: Upload hassio snapshots to Dropbox
To NextCloud: [New Addon] Snap-Shipper - Webdav backups (and probably other ways to later on)