I have a pretty wide variety of items that I use, and everything works well with Z2M and the CC2531.
- Xiaomi Buttons
- Xiaomi Motion Sensors
- Xiaomi Temp/Humidity Sensors
- Xiaomi wall plug
- Osram Lightify GU10 CCT downlights
- Osram Lightify E27 RGBW Bulbs
I did find I had some issues with earlier versions of Z2M, but since the 1.7.x update and newer, I’ve had zero drop outs, or unresponsive items.