Custom Component: Nikobus

OSError: [Errno 5] I/O error

This indicate you cannot reach /dev/ttyUSB0

You have a problem in your setup not related to the intégration. Search on the forum on how to setup USB devices.

It’s normal not to retry as there is a fault in the platform setup

Examples

Connecting USB adapter to a HA installation inside VMware - Configuration - Home Assistant Community (home-assistant.io)

Home assistant VM on VMWare ESXI 7.0 doesn’t goes USB Passthru - Hardware - Home Assistant Community (home-assistant.io)

USB-Bluetooth Passtrough VMware for Yale Access Bluetooth - Third party integrations - Home Assistant Community (home-assistant.io)

Issues with USB(skyconnect) on VMware ESXi - Installation - Home Assistant Community (home-assistant.io)