A NUC is just an Intel-branded mini-PC. The same things that work on a NUC will work on any Intel desktop/laptop/etc.
2GB and 32GB are enough to run Home Assistant but with PLEX, you’ll probably want to increase both a bit.
I’ve got HA running on an i7 miniPC with 512GB storage and 8GB RAM but I’m also running Windows 10 as the main OS, Blue Iris camera software, and HA on VirtualBox (with 2 cores and 32GB dedicated to it).
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