You’ll have to get more specific for you to get a real answer. It all matters what type of heating system, how the zones are controlled, what kind of thermostats, etc. There isn’t a generic flow that can be applied.
Nodered is versatile enough to get you to any configuration you like but a lot of details need to be ironed out. Check out this project that is a total DIY. The control for that will look different if you want to use off the shelf devices.