Yeah. With Tasker, if memory serves, you’ll need a plugin that’ll generate Post calls (instead of Gets), but that’s totally doable. I have Tasker watching alarms on my phone to turn on lights in the house when they trigger.
I keep input_booleans for awake/asleep for myself and my wife. When one is true, some lights turn off in the bedroom. When both are off, all lights, tv, etc get turned off.
Look at the “services” tab of HASS’ ui (bottom of the sidebar - looks like a remote control). Here’s some info on how to find the correct URL to activate anything within HASS: