I have a couple of chromecasts powered by the tv they are hooked up to so they turn off when the TV does. I have a suspicion them going offline may be contributing to the problem but haven’t had time to experiment.
I never considered that the chromecast/s could be adding to the issue - just the Google Home…
The only thing I use casting for in HA is announcements - so at the moment laziness is winning out over wanting to get it fixed 
@mikegrb - Disconnected my chromecast - adding the cast integration back in worked and HA survives a restart now…
Although HA 0.76.1 & 0.76.2 released since my issue started, and me needing to reset my router and re-setup - so it could be that one of those also had something to do with it working again…
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I did the same yesterday so I could get TTS Google Home announcements. So far so good.
Thanks for the “get rid of core.config_entries” it also solved my GUI problem.