Thanks for answer it helped.
I experienced other problems to make tox working so I will put solution that worked for me here for reference.
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Missing some dependencies - had to install following
sudo apt-get install python-pip python-dev libffi-dev libssl-dev libxml2-dev libxslt1-dev libjpeg8-dev zlib1g-dev -
On target device with debian and python 3.4 creating venv doesnt work so I use solution mentioned in http://askubuntu.com/questions/488529/pyvenv-3-4-error-returned-non-zero-exit-status-1
sudo apt-get install python3.4-venv pyvenv-3.4 --without-pip hass-dev-venv source hass-dev-venv/bin/activate curl https://bootstrap.pypa.io/get-pip.py | python deactivate source hass-dev-venv/bin/activate