All Zigbee devices have become unavailable

Hello.
I have a big problem. All Zigbee devices have become unavailable.
I don’t touch HA for 4-5 weeks before.
No updates, no restart.
My setup - Raspberry Pi 4, СС2531 USB, about 20 devices.
I tried updating to the latest version. And restart Raspberry.
No result.
I tried to pair one device - no result.
What’s next?
I’m going to remove ZHA integration, then reboot, then add it again.

How to test СС2531?
Please help.

This is part of debug log:

2021-04-21 21:00:07 INFO (MainThread) [zigpy_cc.zigbee.application] Starting zigpy-cc version: 0.5.2
2021-04-21 21:00:07 DEBUG (MainThread) [zigpy_cc.uart] Connecting on port /dev/serial/by-id/usb-Texas_Instruments_TI_CC2531_USB_CDC___0X00124B0018E2905C-if00 with boudrate 115200
2021-04-21 21:00:07 DEBUG (MainThread) [zigpy_cc.uart] Connection made
2021-04-21 21:00:08 DEBUG (MainThread) [zigpy_cc.api] --> SREQ SYS ping tsn: None {'capabilities': 1}
2021-04-21 21:00:08 DEBUG (MainThread) [zigpy_cc.uart] Send: b'\xfe\x00!\x01 '
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.uart] Frame received: <UnpiFrame command_type=CommandType.SRSP subsystem=Subsystem.SYS command_id=1 data=b'y\x01' length=2 fcs=26>
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.api] <-- SRSP SYS ping tsn: None {'capabilities': 377}
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.api] --> SREQ SYS version tsn: None {}
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.uart] Send: b'\xfe\x00!\x02#'
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.uart] Frame received: <UnpiFrame command_type=CommandType.SRSP subsystem=Subsystem.SYS command_id=2 data=b'\x02\x00\x02\x06\x03\x90\x154\x01\x02\x00\x00\x00\x00' length=14 fcs=218>
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.api] <-- SRSP SYS version tsn: None {'transportrev': 2, 'product': 0, 'majorrel': 2, 'minorrel': 6, 'maintrel': 3, 'revision': 20190608}
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.api] Version response: {'transportrev': 2, 'product': 0, 'majorrel': 2, 'minorrel': 6, 'maintrel': 3, 'revision': 20190608}
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.zigbee.application] Adapter concurrent: 2
2021-04-21 21:00:09 INFO (MainThread) [zigpy_cc.zigbee.application] Detected znp version 'zStack12' ({'transportrev': 2, 'product': 0, 'majorrel': 2, 'minorrel': 6, 'maintrel': 3, 'revision': 20190608})
2021-04-21 21:00:09 INFO (MainThread) [zigpy_cc.zigbee.application] Forming network
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.zigbee.application] Config: OrderedDict([('network', OrderedDict([('channel', 11), ('channels', <Channels.CHANNEL_11: 2048>), ('pan_id', 0x1A62), ('extended_pan_id', dd:dd:dd:dd:dd:dd:dd:dd), ('update_id', 0), ('key', None), ('tc_address', None), ('key_sequence_number', 0), ('tc_link_key', [90, 105, 103, 66, 101, 101, 65, 108, 108, 105, 97, 110, 99, 101, 48, 57])])), ('database_path', '/config/zigbee.db'), ('device', {'path': '/dev/serial/by-id/usb-Texas_Instruments_TI_CC2531_USB_CDC___0X00124B0018E2905C-if00', 'flow_control': None, 'baudrate': 115200}), ('topology_scan_skip_coordinator', False), ('topology_scan_enabled', True), ('ota', {'ikea_provider': False, 'ledvance_provider': False, 'otau_directory': None}), ('topology_scan_period', 240)])
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.zigbee.application] NetworkOptions: <NetworkOptions networkKeyDistribute=False networkKey=[1, 3, 5, 7, 9, 11, 13, 15, 0, 2, 4, 6, 8, 10, 12, 13] panID=0x1A62 extendedPanID=dd:dd:dd:dd:dd:dd:dd:dd channelList=Channels.CHANNEL_11>
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.api] --> SREQ SYS osalNvRead tsn: None {'id': <NvItemsIds.ZNP_HAS_CONFIGURED_ZSTACK1: 3840>, 'offset': 0, 'len': 1, 'value': b'U'}
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.uart] Send: b'\xfe\x03!\x08\x00\x0f\x00%'
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.uart] Frame received: <UnpiFrame command_type=CommandType.SRSP subsystem=Subsystem.SYS command_id=8 data=b'\x00\x01U' length=3 fcs=62>
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.api] <-- SRSP SYS osalNvRead tsn: None {'status': 0, 'len': 1, 'value': b'U'}
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.zigbee.start_znp] Item 'hasConfigured' is valid
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.api] --> SREQ SYS osalNvRead tsn: None {'id': <NvItemsIds.ZNP_HAS_CONFIGURED_ZSTACK1: 3840>, 'offset': 0, 'len': 1, 'value': b'U'}
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.uart] Send: b'\xfe\x03!\x08\x00\x0f\x00%'
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.uart] Frame received: <UnpiFrame command_type=CommandType.SRSP subsystem=Subsystem.SYS command_id=8 data=b'\x00\x01U' length=3 fcs=62>
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.api] <-- SRSP SYS osalNvRead tsn: None {'status': 0, 'len': 1, 'value': b'U'}
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.zigbee.start_znp] Item 'hasConfigured' is valid
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.api] --> SREQ SYS osalNvRead tsn: None {'id': <NvItemsIds.CHANLIST: 132>, 'len': 4, 'offset': 0, 'value': b'\x00\x08\x00\x00'}
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.uart] Send: b'\xfe\x03!\x08\x84\x00\x00\xae'
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.uart] Frame received: <UnpiFrame command_type=CommandType.SRSP subsystem=Subsystem.SYS command_id=8 data=b'\x00\x04\x00\x08\x00\x00' length=6 fcs=99>
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.api] <-- SRSP SYS osalNvRead tsn: None {'status': 0, 'len': 4, 'value': b'\x00\x08\x00\x00'}
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.zigbee.start_znp] Item 'channelList' is valid
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.api] --> SREQ SYS osalNvRead tsn: None {'id': <NvItemsIds.PRECFGKEYS_ENABLE: 99>, 'len': 1, 'offset': 0, 'value': b'\x00'}
2021-04-21 21:00:09 DEBUG (MainThread) [zigpy_cc.uart] Send: b'\xfe\x03!\x08c\x00\x00I'

Same here. After update to latest version (2021.4.6) all my zigbee are unavailable.

Just to add another datapoint I noticed the same thing but after a power failure.