Automating HVAC

Does anyone have experience with smart ducts or registers for HVAC systems? We’re building an off grid house and I’d like to be able to do things like keep the storage area at 50F, but we’ll have one heat source for the whole house. So was thinking of just using a thermostat to control opening/closing either a duct or the registers going to the storage room. I’m not sure if it would be better to go with smart ducting (open/close duct) or smart floor registers. I’m also not sure about good equipment brands in this space, etc. This is a big project so I’d like to get it right up front while we’re designing it. Anyone familiar with this have any pointers? Thank you!