I wanted to do the above because I worry about SD cards failing and part of my reasoning for moving away from a VM on a NAS to a PI4 was to get a bit more stability (ironically).
I just cannot get it to work. I can get the PI4 to boot from hard disk using a standard PI OS. That works fine. My challenge comes when I try to boot from a HomeAssistant image. It transfers to the disk using balenaEtcher fine, however when the PI boots it goes around a loop saying it “Unable to read partition as Fat”.
I have tried a smaller SSD and I have tried a different SSD to USB converter (though I suspect the fact I can do this with PIOS makes this a moot point). I am using the 64 bit image as I noticed the recommended 32bit one did not seem to support boot from USB and the pi is on the 3rd September 2020 released firmware.
Anyone achieved this and got any ideas?