Byte operation for data from ser2net server

Hi, need help.
I did not find how to perform byte operations with the raw data received from the server ser2net. Found a topic, the person also did not receive an answer to a similar question. Is it possible to convert tcp data to integer?

on the screen there is an error and the last attempt to somehow convert the data. But the python handler tries to see some headers in the received bytes immediately after receiving.
I only need 4 and 5 bytes - this is integer16