CM4 eMMC too small, can I install the OS on an NVMe?

I managed to snag a CM4, but it only has 8 GB of eMMC storage. Based on my current installation, not nearly enough to have my Home Assistant OS on it. Is it possible to install the OS on the NVMe and have the installation ignore the eMMC? It appears from what I’ve seen that you can install on the NVMe with a CM4 Lite, but wasn’t sure if it also worked with an eMMC CM4.

I think I found the answer in the installation manual (RTFM):

  • Advanced: Forcing installation onto the NVMe SSD when using CM4 with eMMC:
    Press the blue button while the yellow LED is on constantly (during the 5s window, see next step).

https://yellow.home-assistant.io/poe-nvme/

Is there any disadvantage of doing it this way?