Doubt about MCP23017 integration

I rehearse the question in different terms, if anyone has used + MCP23017 with I2C raspberry (no esphome).
I have a perfectly functioning mcp23017 with the address 0x20.
I am trying to add another one with address 0x21 in parallel to the first one.
The question is this: is it possible to do this?
I have been trying for days but HA does not detect the 16 entities and therefore I have the doubt that the “MCP23017 I / O Expander” integration supports only one.
Thank you