Wire a power cable to the Hub, fire it up and pair all your TRVs and Room Thermostat to that. There is an integration for the Drayton Wiser kit. You will be able to control all the TRVs and would make more sense than playing with an incompatible ZHA/Z2M integration.
FYI when you twist the knob the valve boosts, it send a message that it has been boosted up or down. It sets the target temperature to current temperature +/-2 Celsius. And should open or close the valve accordingly.
Your TRVs must be on a firmware where the valves required a response from the Hub to change the state of the valve.
The Drayton Wiser integration’s topic:
A fair note, the Wiser Hubs have an issue as they loose wifi connections recently, but Wiser is looking at the issue currently.
PS.: I went down the same route, first developing a Device Handler in SmartThings then moving to Z2M. But at the end, I fired up the Hub and I do not regret it at all. It works really well. And it does not Matter (
) that it is the 4th Zigbee network in the House. 