I do not use “base_url” has been depreciated in HA 0.110 .
HTTP - base_url is deprecated and replaced by an internal_url and external_url core configuration setting "in the UI ". - (@frenck - #35224) (basic config docs) (http docs)
Concerning the guides , for the moment I use the HA doc for Duckdns addon as it should be sufficient for DDNS and LetsEncrypt certificate
About
Duck DNS is a free service that points a DNS (sub-domains of duckdns.org) to an IP of your choice. This add-on includes support for Let’s Encrypt and automatically creates and renews your certificates. You need to sign up for a Duck DNS account before using this add-on.
Remote access is working using http + 2FA for the moment with Duckdns but I do not want to switch to Duckdns+LetEnscrypt + NGINX before basic configuration with Duckdns works (https)