First steps? Node-Red + Zwave + Zigbee etc

Hi, I installed Hass.io as an LXC container on my Proxmox server. Here I also passed a Zigbee and ZWave USB stick through at the same time. I want to control and automate everything via Node-Red in Hass.io.

Now the question is how do I best start here? What is the easiest way to configure everything easily?

Should I install Zigbee and Z-wave in the configuration via Integreation or should I install and configure both under Addons? And which Z-wave should I use exactly? I would also like to integrate my devolo thermostats. Do I also have to install the devolo add-on first and then integrate everything?

Thanks in advance for your feedback