Front End loads, but nothing responds to clicks

When I access HA on the front end, Lovelace loads as expected, but from the bookmarks bar down, none of the entities, links, tabs…nothing below the bookmark bar will respond to clicks.

It’s like the page freezes immediately.

Console shows no errors in chrome. Same result in Safari.

Any ideas on how I can troubleshoot this if I can’t get into HA front end at all?