Generic Thermostat - "Real thermostat" and remote temp sensors

How do I connect together a bunch of BLE temp sensors (already feeding into HA) to a “real” thermostat?

I assume generic_thermostat is what I need but I can’t figure out how to take the inputs from across the house and how I get them to affect the real thermostat. I’d like to leave the real Venstar T2000 units on the wall because of WAF - but how do you recommend I go about calling for heat or cool (I live in NC, USA)? These thermostats accept curl commands but am I best modifying the target temps or what? Clueless over here. Help!