Yea I did check it out. Seems to be a widespread issue that’s likely related to network manager. Been trying to figure it out, just not sure why it stopped working after 4.0.0.
EDIT: This might help some: I tried the method of installing 4.1.6 then going to the Configuration page of the add-on and saving the Network section. AdGuard now shows the proper listening address and seems to be working fine now.