Yes it is, I’ve just managed to get it working
follow these steps to set up a cloudflared tunnel from a docker container (just use milgradesec/cloudflared instead of cloudflare/cloudflared): HOW TO deploy Cloudflare tunnel on a Container. (the raw way) - YouTube
Then follow these steps to get it to work with HA: HOW TO: connect Cloudflare tunnel to home assistant and node-red. - YouTube