Integration does not survive reboot and deleted old integration are back after reboot

Hi, I have been strugling for a while to fix a very frustration issue.
I have several integrations and are also found in ./storage/core.config_entries
If I add a new integration it works fine, core.config_entries does not update and after a reboot the integration are gone. If I delete integrations they disapaer immidelty from screen but are back after reboot and was not removed from core.config_entries
No error messages that point me in right direction.
Any help are much appreciated.

Issue remains on latest 2022.10.
Any idea were to troubleshoot?