Is it possible to invert the Pi's display?

New at HA here…I see xrandr is not available…

I’m assuming you are talking about Home Assistant OS.

xrandr is not available because there’s no X server.
You’ll need to rotate the framebuffers.

echo 1 > /sys/class/graphics/fbcon/rotate_all
  • 0 - normal orientation (0 degree)
  • 1 - clockwise orientation (90 degrees)
  • 2 - upside down orientation (180 degrees)
  • 3 - counterclockwise orientation (270 degrees)

To make this permanent, you should be able to configure uboot by adding fbcon=rotate:1 to bootargs.

Please note that I have NOT tested this.