Logitech Harmony Issues

I have suddenly started experiencing issues with my Harmony Smart Hub remote. Rebooting HA seems to solve the issue for a few hours and then it starts to occut again.

Oddly, the issue only seems to be with the remote.turn_on and remote.turn_off command to start stop an activity. using remote.send_command for say volume+ still works absolutly fine, so cannot put it down to a connectivity issue.

There are no issues repported in the log. Is there any components I should turn on in the logger to help diagnose the issue ?