The answer is a no - at least not to my knowledge.
With the ‘nginx Home assistant SSL proxy’ add-on, along with DuckDNS add-on, you would be able to expose you HA to the internet. The intension here is to get it up and running with minimal user configuration.
And if anyone (like you) wants a step further, to expose additional locations to the internet, then you probably would go with the NGINX Proxy Manager (or Caddy, FWIW) add-on. Obviously more tweaking would be required. Search around you probably would find more discussions.
Could the NGINX Proxy Manager handle Let’sEncrypt DNS-01 challenge these days? I didn’t check for a while now.