No USB devices working after Core 2021.5.1 update

Configuration
1

I am running HA on a Raspberry Pi 4 with 4Gbyte of memory. I have 3 devices attached to USB ports: a Conbee II Zigbee bridge, a Wyze sensor bridge and a Coral TPU. All were working perfectly until I updated the HA Core to 2021.5.1. Now none of them work.
I have updated to Core 2021.5.2 and the same result applies

To give an example for Zigbee, here is the log output:

Logger: homeassistant.components.zha.core.gateway
Source: components/zha/core/gateway.py:157
Integration: Zigbee Home Automation (documentation, issues)
First occurred: 12:56:17 PM (5 occurrences)
Last logged: 12:57:37 PM

Couldn't start deCONZ = dresden elektronik deCONZ protocol: ConBee I/II, RaspBee I/II coordinator
Traceback (most recent call last):
  File "/usr/local/lib/python3.8/site-packages/serial/serialposix.py", line 322, in open
    self.fd = os.open(self.portstr, os.O_RDWR | os.O_NOCTTY | os.O_NONBLOCK)
FileNotFoundError: [Errno 2] No such file or directory: '/dev/serial/by-id/usb-dresden_elektronik_ingenieurtechnik_GmbH_ConBee_II_DE2430101-if00'

During handling of the above exception, another exception occurred:

Traceback (most recent call last):
  File "/usr/src/homeassistant/homeassistant/components/zha/core/gateway.py", line 157, in async_initialize
    self.application_controller = await app_controller_cls.new(
  File "/usr/local/lib/python3.8/site-packages/zigpy/application.py", line 69, in new
    await app.startup(auto_form)
  File "/usr/local/lib/python3.8/site-packages/zigpy_deconz/zigbee/application.py", line 65, in startup
    await self._api.connect()
  File "/usr/local/lib/python3.8/site-packages/zigpy_deconz/api.py", line 245, in connect
    self._uart = await zigpy_deconz.uart.connect(self._config, self)
  File "/usr/local/lib/python3.8/site-packages/zigpy_deconz/uart.py", line 142, in connect
    _, protocol = await serial_asyncio.create_serial_connection(
  File "/usr/local/lib/python3.8/site-packages/serial_asyncio/__init__.py", line 445, in create_serial_connection
    serial_instance = serial.serial_for_url(*args, **kwargs)
  File "/usr/local/lib/python3.8/site-packages/serial/__init__.py", line 90, in serial_for_url
    instance.open()
  File "/usr/local/lib/python3.8/site-packages/serial/serialposix.py", line 325, in open
    raise SerialException(msg.errno, "could not open port {}: {}".format(self._port, msg))
serial.serialutil.SerialException: [Errno 2] could not open port /dev/serial/by-id/usb-dresden_elektronik_ingenieurtechnik_GmbH_ConBee_II_DE2430101-if00: [Errno 2] No such file or directory: '/dev/serial/by-id/usb-dresden_elektronik_ingenieurtechnik_GmbH_ConBee_II_DE2430101-if00'

Can anyone tell me what is happening?

2

Try restarting the host machine (supervisor / system panel if running HA OS).

3

Once again I owe you @tom_l. I restarted everything else but not the host! That seems to have solved the problem. Thanks so much

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