Remove/ignore entities on the fly?

My wife often turns off the surge suppressor overnight that powers many of my media devices. As a result, HA will repeatedly send errors errors to the log stating it can’t connect to Roku, for example. The amounts to hundreds of messages and seems to cause network/stability issues. I want to be able to shut off the surge suppressor and even considered formally adding this to my setup by installing an Wi-Fi outlet.

Is there a way to unload the affected entities from my setup so that HA doesn’t continue searching for them when I know they’re unavailable? Obviously, I don’t want to modify and reload my HA setup on a nightly basis, so I would need an on-the-fly method.

I don’t believe this is possible.
You could always change your logger options to ignore these entities so as not to bloat your logs, but the entities will stay enabled…