It is a well known problem that USB3 ports generate interference around 2.4GHz and it is not recommend they be used as they can interfere with zigbee packet reception. See: Zigbee network optimization: a how-to guide for avoiding radio frequency interference + adding Zigbee Router devices (repeaters/extenders) to get a stable Zigbee network mesh with best possible range and coverage by fully utilizing Zigbee mesh networking