Split FE from BE up to the root... is it possible?

Hello everyone,
I am new to the forum and I’m just looking at the code of the core and FE. As a developer I’m used to divide business logic from presentation logic… and do not even share the main process.

So, according to your knowledge, it is possible to split the FE from the BE and run it in 2 different services?

Something like: FE singlepage application that run on nodejs/apache/nginx, BE remain as it is, and all comunication only via https/wss

is it easy path or it is a catastrofic event to avoid?