Taking a backup of ZHA using bellows on Home Assistant OS

If it works then the easiest would be to use the blueprint for zha-toolkit as then backups could be done online without stopping ZHA

https://github.com/mdeweerd/zha-toolkit

https://community.home-assistant.io/t/daily-zigbee-coordinator-backup-blueprint-znp-ezsp-bellows/377149

https://community.home-assistant.io/t/zha-toolkit-toolkit-providing-low-and-high-level-zigbee-commands-through-zha-zigpy/373346

Otherwise you for now would need to stop/disable ZHA to perform offline backup via bellows directly:

https://github.com/zigpy/zigpy/wiki/Coordinator-Backup-and-Migration

https://github.com/zigpy/bellows/blob/dev/README.md#nvram-backup-and-restore

PS: Regardless consider vote to show interest → ZHA integration to do nightly backup of both Zigbee Coordinator adapter/dongle/stick and Zigbee database?