"ttyUSB0 failed to get modem status: -110" on Home Assistant OS in VirtualBox

I use HassOS on VirtualBox and always have such messages when USB device is connected. After some time the device does not respond at all - a USB reconnect on VirtualBox helps.

Where could be the problem?

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I’ve discovered that the issue was caused by VM backups. To resolve it, you should detach the USB before starting the backup, and then reattach it after the backup is complete.

I had the same errors on ESXi, I fixed it by changing the virtual USB controller to 3.X instead of 2.0. Not sure if that is applicable in Virtualbox but you can check.

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