Two pis integration

Hi to all.
I have a question regarding the installation on the RPI.
I have HA working on RPI4 whit no problems.
I also have a RPI3 whit 2 HD’s running headless software like FTP server, samba, syncthing, some crontab an other software.
My question is can i integrate but PI’s in to one. And add the two HD’s?
I have try installing HA i think is call virtual environment (venv), got it working but in that version i don not have the supervisor part. So i deleted, have not try other way
Thank all.

If you are wanting to run home assistant plus other server software, the best be wouold be to use a supervised installation of home assistant.