Recently migrated from RPI3 to NUC. RPI3 was running the AIO; NUC is running Ubuntu 17.10 (16.04 LTS didn’t like Kaby Lake) with a docker container for HA.
Migration was really smooth; no real issues. Moved my Aeotec ZWave stick and files and it all came across ok.
Also HO-LEE-SHIT is it faster. Night and day in response time. I always felt that HA would be pokey as waiting on Zwave communications but I can tell you more CPU has certainly helped everything. Much snappier in ways I’d not expect.