Have you updated the firmware on the conbee recently, if not it might be worth doing so first.
I had a conbee2 for years and never had an issue, until approx 6-8 months ago when almost every time I restarted HA the conbee would be unavailable on restart.
I would get it back by either doing a hardware reboot OR disconnecting and reconnecting the stick.
I updated the firmware a few weeks ago (was one version behind) and touch wood, so far I have not had the issue.
Having said all of that I do know this is a very common issue reported with the conbee2.
I updated it via win10, take a look here, you are supposed to be able to update it via the deconz software but I have tried 101 times and the update option never shows for me: