ZWave breaking changes RC 2022.6?

After upgrading to RC 2022.6, my ZWavw JS no longer sees my devices. I am running Z-Wave JS to MQTT version: 0.42.0

I am getting these new errors:

Error: Failed to open the serial port. Error Resource temporarily unavailable. Cannot lock port (ZW0100)
Error: Driver: Failed to open the serial port: Error Resource temporarily unavailable. Cannot lock port (ZW0100)

Any troubleshooting tips would be appreciated. Maybe reboot my host?

Yes, this fixed it.