Find a way to deal with, open a local connection to shell and use nmcli (one shot)
nmcli connection modify "Supervisor enp0s18" +ipv4.routes "192.168.20.0/24 192.168.10.250"
Or try in interactive mode :
nmcli con edit "Supervsisor enp0s18"
nmcli> set ipv4.routes 192.168.20.0/24 192.168.10.250
nmcli> save persistent
nmcli> quit
I tried this and then reboot (not sure if needed) and magic, it worked.