Technically, it is possible to connect some additional sensors directly to GPIO and trigger the wlopm --on * command (which is used to turn on the screen), but that would require wiring and custom programming.
The screen can be put into sleep mode using the Raspberry Pi’s built-in screen blanking function (e.g. blank screen after 10 minutes) and woken up again by tapping it once. Alternatively, the method below can also be used.
With the mqtt integration it is possible to turn the screen on via Home Assistant. The only thing required would be a Home Assistant automation and an existing presence or motion sensor. e.g when presence is detected, turn the screen on, turn off when no presence or after some timeout.
Additional the screen brightness may also be adjusted if the sensor provides some light (lux) measurements. e.g. dim the screen brightness down at night.